The 19. 5's don't contribute to the stiffness. The tire reinforcement does. The F's are stiffer than the E's and the G's are even worse. The extra weight of the wheels is harder on the suspension and the steering. The safety factor and the reliability are nice though. The sway and lean is reduced when stepping up also. . but that is due to the tire reinforcement also, has nothing to do with the suspension. There are no really agressive tread patterns for 19. 5's either. If you start seeing cupping on the front treads, more so than with your stockers... Odds are it is due to the added weight of the wheels and has nothing to do with your alignment.
How do I know??? I went thru all of this. I now run 17's and will use my 19'. 5. s on a custom 2wd. It is amazing how ignorant 99% of the tire shops are. Don't let anyone tell you/convince you that your tires wear poorly because it is a Dodge, dually, diesel, heavy truck, or anything else stupid. There are reasons.