If you tow and especially if you have an automatic, you could "over gear" meaning you might not be able to tow well in OD. I run 285/75/17 when not towing and it is nice but I struggle towing to keep my standard trans in 6th. I have my stock wheels with stock tires that I put on for long trips. My OD is .74 (6th)
As said above, the off set isn't correct for your truck.