I don't know, I've got over 500,000 miles on my last two trucks with no lub problems. My present truck will roll over 107k tomorrow after just over a yr. That kind of mileage is why I use the bypass filter plus the Amsoil. If I changed oil every 3000 miles, I'd be changing every couple of weeks. Being on 24 hr call, I just don't have time for it.
Yes, Joe is right, there is a very small orifice in the mounting head of the Amsoil single bypass setup. I don't know what the pressure loss would be, but it wouldn't be very much.