Also, while we are at it we might as well debate what the best hair color for a wife.
There are so many factors to consider. The 3. 54 and the 4. 10 will be in the sweet spot at "normal" driving speeds, albeit one at the top end and the other at the bottom end of the range. The transmissin makes a great deal of difference in the choice. The high gear ratio is . 69 in the auto, . 71 in the six speed and . 73 in the five speed. There is more difference in final raios between a auto and a five speed (6%) than there is between a 3. 54 and the new 3. 73 (5%).
Tire size is also a great deal of differece. There is 5% difference between the stock 245/75/16 tires and the optional 265/75/16 tires. The "tall" tires can add another ten or 15 percent of gear.
If he is going with a manual transmission, stock tires, and will do a lot of light towing, under 15K GCVW, or bob-tailing I would go with the 3. 54. Also, it would be the right choice if he likes to drive 75 or 80 MPH routinly on the interstate.
If he wants an auto, big tires, or will tow near max rating often I would go with the 4. 10s. The six speed does offer enough gears that he could run in 5th while towing 20K loads and still keep his 3. 54s for running empty.
One man's opion. It's worth what it cost you!!
Bryan