Hi Clayton,
Yes, it's perfectly safe. I run B100 in mine during the warmer weather. Running about B20 now.
There will be a few differences.
Different exhaust smell.
Less soot under power(up to 70%).
Maybe lower mileage (varies with users, mine goes down with B100 but is highest with nearly any mixture)
More white smoke on cold starts for a few seconds.
It will definitely NOT lower gel points. It raises them, but not enough to worry about at B20 levels. (Edited, I wrote B100 instead of B20 by mistake)
Injector and pump lubrication go up significantly.
Joe