My entire EGR system was removed for about 360,000 miles and other than the CEL being on nothing else happened. No limp mode, no issues. I don't think it had any effect on the DPF, at least not any negative effect as my original DPF lasted around 360,000 miles too. The only thing I noticed after removing the EGR was my higher sense of confidence in the truck, knowing it wouldn't strand me with a burned out EGR cooler again.