Generally speaking, all 3/4 ton trucks have a heavier frame than a half ton.
One other important factor in the carrying of weight is the RE. The half ton has a semi floating axle, while the 3/4 ton has a full floating axle.
In otherwords the half ton axle supports the weight on the axle bearing on the end of the flange. As these trucks go, its usually a 6 stud wheel. On the 3/4 ton truck, the weight is supported on the axle tube or trunnion shaft. Being a larger dia. axle, this is an 8 stud wheel. If an axle should break on a half ton truck, one could lose the wheel. On the full floating axle on the 3/4 ton, if the axle breaks, the wheel is still independent from the axle as the axle tube or trunnion shaft supports the bearings (two) locked in.
One seldom hears of this breakage now days as the materials have improved over the years. International P/U's were famous for braking axles in the old days.
One can see a lot of half ton trucks towing travel trailers, as there is an old trucker's saying that one can tow more than he can haul.
With a fifth wheel or camper, there is more weight on the bearings. Thats why 3/4 ton trucks and up are considered the safe bet.
This does not really address the frame size but the frames are different either from the flange width or depth.
Chuck