Ever since we got the LB7 service trucks... it was always a common phenomenon. . (sp?) that either you couldn't keep it out of the shop, or it never went. I've been driving one in my 03 company truck for about 200k miles now, and its on its 3rd engine. To be honest, i've lost count of the # of injector sets, injection pumps, water pumps, turbochargers, alternators, rear housings leaking coolant that require the trans to be pulled... and complete engines that we've went thru on these five trucks. There is a whole list of other stuff, but its on the GM part of the truck... .
That being said, none of these are overloaded, but they are loaded very well... average 20K lbs. every day. Our 05, 06 and 07 models have had very few issues, actually as far as engine issues, I think we've lost one turbo, and each has lost a water pump... but other than that, very reliable as far as the engine goes.
Personally, I think if you keep a close eye on the oil for the presence of fuel, and the LB7 isn't being stressed out with high loads on a regular basis, it will provide good service.
Keep a good eye on the oil level. The LB7 seems to be prone to filling the crankcase with fuel... which is a bad situation for the bottom end...
Anyway. . just my . 02... .