I bought an '03 used a few years back, and loved the truck, which exploded this winter, I might add. But when I first got it, it had a 20lb propane tank welded in place of the muffler, with a pipe welded into the side to exit out in front of the duals. I didn't care for that, and bought a SS exhaust system from Summit. At the initial install, I installed the straight through muffler backwards, so it would sound cool, right? Well, I towed a trailer the next morning to take my horse to the vet, and when I unloaded him, he kept shaking his head and cocking it when I talked to him. The poor sucker was half deafened!! I made it home, turned him out, and went straight to my shop to reverse the muffler. It's still plenty loud, but it won't deafen the animals in the trailer anymore. Also, if you take the muffler completely off, it will definitely be heard in the cab. You'll have to turn your radio up at least three more notches to hear it the same. If you like the way it's quiet now, I wouldn't do take your muffler off. I don't think you will see much performance gain. As for your friend, I'd bet the reason he's getting better mileage is that he can "hear" himself getting on the throttle, and is backing out of it, thus the better mileage. Just my opinion.
God bless,