Here is some great info on the subject:
In most stock vehicles with stock tires there is seldom a risk of a burned gear set. For those of us who modify and use our trucks, there are many situations that can contribute to burned gear syndrome. Motorhomes, TOWING, tall tires, and high numeric gear ratios can all generate a lot of heat and cause the gear oil to break down. The greatest damage to a new gear set results when it has been run for ten minutes or more during the first 500 miles and the oil is very hot. Any heavy use or overloading while the oil is extremely hot will cause it to break down and allow irreversible damage to the ring & pinion.
In order to make them run cooler and quieter, new gears are lapped at the factory. However, they are not lapped under the same pressures that driving creates. The loads generated while driving, force any microscopic high spots on the gear teeth back into the surface of the metal. This is called "work hardening". Work hardening is similar to forging in the way that it compresses the metal molecules into a very compact and hard formation. This can only be accomplished if the metal surfaces are lubricated and the gear temperature stays cool enough that the molecular structure does not change. If the temperature of the metal gets hot enough to change the molecular structure, it will soften the surface instead of hardening it. This may seen like a balancing act but it all happens easily & passively as long as the oil keeps the gear cool while it is breaking in. Some of the synthetic oils on the market today can help a gear set live longer. These oils will continue to lubricate at temperatures where many crude oils break down.
Even with synthetic oils, break in is still recommended. After driving the first 15 to 20 miles it is best to stop and let the differential cool before proceeding. Keep the vehicle at speeds below 60 mph for the first 100 miles. It is also recommended to put at least 500 miles on the new gear set before heavy use or towing. During the first 45 miles of towing it helps to go about 15 miles at a time before stopping to let the differential cool for 15 minutes before continuing. This is necessary because not all of the gear tooth is making contact until it is heavily loaded. When towing, the teeth flex to contact completely, and cause the previously unloaded portion of the teeth to touch and work harden. All of this may seem like paranoia, but it is very easy to damage the ring & pinion by overloading before the teeth are broken in. If you take it easy on a new ring & pinion and keep it full of high quality oil, it should last a lot longer.
Do you really want to chance having problems with that expensive new truck? Gears require proper break in. Don't listen to haphazard responses and I would guarantee that not one of them is a Metallurgical Engineer. Why risk it.