In the factory configuration, there is a check ball or valve on the inlet side of the block mounted heat exchanger. This is the hot line, or the output of the trans.
The purpose os this valve is to prevent drain back. Although, it doesn't even do a good job of that. Many performance transmissions shops will remove this altogether as it may become stuck and stop the flow of fluid.
If you remove it, and your trans does not have the lube in Park mod done, you will need to put the truck in Neutral for a minute of so before starting out. This will get lube in the circut and prevent and problems.
Dave