Lockup is TC lockup, that th eusual problem at that speed and steady throttle when the truck ages. OD bouncing has different results and usually different sources. You need to figure out what problem you have first.
Lockup clutch bouncing will give you a 200-300 rpm fluctuation, OD bouncing is more like 800-900 depending on how fast you are going and how much throttle is being used.
Lockup clutch problems are the usual culprit and can have many sources, but, the main problem is noise in the wiring harness that the PCM interprest as a signal to drop lockup. It could come from the alternator, batteries, bad grounds, installed aftermarket equipment, or a bad APPS signal. You have to approach it systematically or it will drive you nuts and cost big $$$ for no result.
Typically the place to start is the batteries and grounding points. Make sure your batteries are both good, tested with a good load tester. Make sure all grounds are tight and clean. Scraping them is advisable. Make sure you battery cables are clean, tight, and have no internal issues. The cross over cable can be problematic and it needs tested for resistance to see if it is bad inside the clamp. Same with battery cables. A lot of issues stem from the noise created by a bad connection inside the clamp.
Next step would be removing the ground wire from the passenger side battery and the alternator charge wire from the control harness. Thes 2 wires are the source of the electircla interference and simply moving them will frequently solve the problem. The alternator charge wire gets cut at the alternator and reroutes over the radiator support to its anchor point below the driver side battery. The passenger side ground wire gets cut and moved tot he firewal then over to the drive side of the engine. It connects to 3 gounding wires in the harness for the PCM and ECM so find that junction and make your connection there.
The alternator would be my 2nd to last piece to change if it is charging well. Don't buy a reman as they seem to be as noisy. A high quality new alternator is the best route and relatively expensive so save it for last.
Last resort if nothing else works, a triple disk TC. They take long enough to lock\unlock that signal noise usually does not effect them.