You of course have the age old choice - Dino or Synthetic?
Then you chose the weight of the oil. If you will tow regularly, a heavier weight oil is recommended, and many would say go synthetic for sure if towing a lot.
I personally switched to Amsoil Series 2000 75W-90 in both differentials. They also have a heavier weight at 75W-140.
Royal Purple and Redline also make well respected synthetic oils & lubes, not sure of their precise weight offerings though.
Whoops - forgot the final question you asked. Most people have posted that if you go with a synthetic lube, you likely won't need friction modifier. I don't use any in mine. I have seen a couple poeple post that even when using synthetics, they needed a friction modifier... . I would say if you go synthetic, do not add any modifier at first, drive the truck a bit and listen/feel for chatter from the rear diff, and then add modifier if needed.
Tom