There are lots of posts on this subject. I read most of them.
a. Camp 1. Most "oil burners" are brand-loyal dino users (take your pick Delo, Rotella, Delvac) and change oil on average at 5,000-7500 miles. No problems at all. Billions of miles.
b. Camp 2. Amsoil users are a very loyal bunch. Most of them are using bypass filtration, oil analyses, and extended change intervals. I've read of some issues with some aftermarket bypass systems, but mostly positive feedback. I'm too chicken to go there while under warranty (if ever).
c. Camp 3. Other synthetics, using original in-line filter. I use the Fleetguard Stratopore. I just switched to Mobil 1 5w40 @ about 25k miles, long enough to run in my engine on dino oil (Delo400). There are other good brands, but I am a long time loyal Mobil 1 user. I'll report on my performance down line (ie mpg). I plan on running this oil to 10k miles as a matter of course. 10k oil analysis posts have been positive for synthetics in general. 10k is double my normal 5k interval, so the cost is just about a wash compared with dino oil. The engine turns over easier when cold. That is what you get with the 5w syn as compared to 15w dino. It's the main advantage of synthetic. Another is the turbo. Synthetics (PAO's) won't coke up at high temp as easily as dino oil. It may be simply preference, but I just feel better knowing that I have Mobil 1 in my crankcase.