Yes. Any fault that will light up the check will cause your emission system to not regenerate. If you go long enough, you will time out and the truck will derate and eventually not be drivable.
I’m sorry to give the news, but I see this very often in my work with light and heavy class diesel trucks.
I’m reading on this forum, that there may be aftermarket parts available. I personally would stick with OEM parts, but in this case it may be worth looking into.