If you keep them on stock wheels, that will not require a lift, so the truck will only rise about 1. 75 inch. (Aftermarket wheels usually stick out more and hit the cab when you turn, which require a lift). Your aerodynamics won't be as bad as going with a lift kit, and your mileage, if you keep them inflated hard will be about the same, maybe barely better.
But if you drive at 70 or above, empty a lot, the engine will rev just like the 3. 73 axle, and that may make you happier with the noise. Acceleration from a stop will be a little slower.