I'm in Minnesota, and the stations around here just started selling winter blend in the last couple of weeks after a cold snap. Personally, I stay away from the winter blend as long as the outdoor temperatures stay over -10* F but I do treat with Power Service during the months when the temperatures can go below freezing. This keeps the injectors cleaner, keeps the fuel from gelling, and helps to disperse any water that might be in the fuel. I also treat my fuel about once a month during the summer months, mostly to clean up the injectors.
The weekend before Christmas I had number 2 fuel (non-winterized) with Power Service added to it, and it was -8* on Sunday morning when I got back from Chicago with a load of liquid sugar (bigger Cummins). The CTD in the pickup started right up, was not plugged in, and had been sitting since Thursday. Oo. Ran like a top. Mileage had been right around 18. 5, but did dip a bit during the colder weather, down to about 17.
A couple of days later, I filled the tank with what was labeled as a 70/30 winter blend. Mileage dropped to 16. Now, several days later, with warmer weather, (in the 20's and 30's) the mileage has climbed back up to 17. Next fill will be straight #2 again, as long as the weather holds. When the forecasts start pointing at subzero cold again, I'll start putting in winterized fuel again.
Incidentally, we see a mileage drop in the over the road trucks during colder weather, too. Some of that drop is attributed to more idling time for cab heat, but the below zero temps bite into it even more. Everything turns harder in the colder weather, especially the tires, requiring more power, and more fuel.
Just my $. 02 worth. Hope you all have a great New Year!