Clearance is tight for a 5” downpipe and production tolerances would make it difficult to mass produce such a downpipe. The bigger the turbine wheel and the outlet flange, the more the turbo is going to benefit from a 5” downpipe. On my 1997, I found that 5” helped once the engine was over 570 HP and that spoolup did not seem to be hurt at all. This effect makes sense, because once the gases have expended energy within the turbine and wheel, the faster they expand and get out of the way, the better. There is a lot of turbulence, sort of like what you see in a bathtub drain. The gases are also hottest as they come out of the turbo. These two situations mean that the biggest benefit from a 5” exhaust will be at the downpipe.