I just made my first long run, 850 each way, across the desert, and through the mountains, Interesting part was that I just had the TSB for the reflash done the day before I left.
Before the reflash, I'd see 18. 2 tops running empty on flat highway. The overhead was 16. 3, but I'm on 315's and I haven't corrected the speedo. Corrected for the tires, the overhead would have been 17. 6.
On the trip, the best I saw was 21. 8 @65 mph by hand, mixed hills & flat @ about 70-75 was 18. 8, and hard up and down was 17. 8. The overhead was closer after the reflash on all cases, and was actually higher doing 80 across the desert. The overhead was 18. 9 with no correction for the tires while actual was 18. 8. Just turned 8k on the truck.