I've been running the Toyo's now for about 8 months. We ran them in the snow, down through Baja, on local roads, etc. I really like them. They are beefy! The hardest part was figuring out the right pressures to run in soft sand. The E rating makes that side wall a little stiffer than my old tires, so I had to run a little softer in the really deep sand.
We did plenty of hard miles off road in Baja with no problems. We actually cracked a wheel, without flatting the tire.
We are off to Baja again in a few weeks to "test" them some more.