My wife has gotten into the habit of leaving her keys in her car when it's in the garage. She recently bought a new Grand Caravan. In the first few days, we had trouble with the battery going dead. I charged it once, the second time we took it back to the dealer. Dealer said there was nothing wrong, it just needed a charge. I thought for sure we would be going back in a day or two. To my surprise, everything was fine . . . but only for a month or so.
Then it happened again. Dead battery after sitting less than two days. We took it back to the dealer again. They put in a new battery. That evening, I was talking to a friend that works at the DCX Proving Grounds. He asked if the key had been left in the ignition. The answer was yes. He said that in some cases, they have seen a battery drain from the key simply being in the ignition. He wasn't sure about the root cause or what action was being taken.
Try leaving the key out of the ignition for a few days and see if they retain their charge. Then put it in for a few days and see if they go dead.
Sorry for the long post.
Ken.