It's a PITA for sure. I don't mess with the wheel well though.
Tips: 1) there is receptacle in bottom of filter 1/2" or 3/8" use to loosen but NOT tighten the canister, need extensions & a wobble too 2) I went to lowes & got a plumbing fitting & extra tubing to extend the drain hose 3) disconnect the WIF sensor 4) open the WIF drain - not much comes out 5) Then loosen the canister slowly - a lot of fuel comes out 6) crawl into the engine compartment from the top & remove the canister 7) install new one.