I read a Cummins article somewhere that said as far as they were concerned, you "drive it like you stole it".
As long as you keep it below red line, it will be fine.
As mentioned, when the RPMs start up above 2200 the MPG heads south in a hurry.
60 mph = 16. 0 mpg for me
95 mph = 9-10 mpg empty no tail gate