I'm betting you have the caliper and axle nut off and can't get the rotor/hub assembly off. (am I close?)
If you don't have the axle nut off, crack it loose with the truck on the ground and wheel still on. 1 11/16" socket (if I'm remembering right) and long breaker bar.
There are four 12 point socket head bolts on the backside of the steering knuckle that hold the whole mess together. Once those are out, I put a 3 jaw puller on the center flange of the rotor and apply some tension. It is rusted togethter usually, and some use of a rust buster might help. You don't want to use the puller to pull the rotor off thoug because you can split your wheel bearing. (it's not supposed to come appart--PITA to press back together)
In the spot where the caliper was, I was able to pry in a small slot (next to dust shield) with a long screwdriver to help get it appart. Some guys have had luck replacing the bolts in the backside (loose) and wailing on the heads to drive it off.
The rotor sort of hides the whole thing, but it will make more sense when it's off. With it off, you'll have a large hole (a bit larger than your U joint yoke diameter to pull the axle out.
If it's the left side, either jack it high to tilt it above oil level or remove some of the gear oil. When the axle shaft comes out, you will get some in the axle tube. It's hard to clean out, and it will drip for months until it's gone.
Good luck with it. Give me a call if you want (I'm in the travel companion section)
Pete