Mine did it once last summer. Was about 50 miles from home at the end of our trip and "ding-ding", zero fuel per guage. Pulled over, turned engine off, checked for holes in tank since I knew I had at least 1/2 tank, started back up and everything was registering normal. Threw two codes, can't remember which ones, something about low and high signal from sending unit. Went to dealer and they couldn't find a problem, but said they have heard of it before.
I have a 70 gallon Transfer Flow tank in the bed of my rig and was concerned that the aux tank pump wouldn't stop pumping at 3/4 tank if the sending unit wouldn't register it. So far all is OK.