If you mix the two coolants, I believe it causes the mixture to become thick and gel like. If i remember right, you are only supposed to use the dexcool antifreeze in approved applications. There was something about it being very corrosive on certain metals that were in older cooling systems. So if you run it in an older car, you might have issues. I however have friends that run it in their cars(70 nova &71 camaro) and neither of them have had issues over the past 2 years they have been running it.