Isn't peak cylinder pressure the main gasket-life determination factor, not boost pressure? If you advance your injection timing, you'll increase your peak cylinder pressure, because fuel is burning that much sooner. But if you also increase the injector pop-off pressure, you will retard the timing some, thus reducing the peak cylinder pressure. If you run nitrous, you'll greatly increase your cylinder pressures unless you retard your timing, because the fuel ignites a lot sooner.
This is the main reason common rail systems will outperform mechanical systems; injection timing can be controlled far better. It should be possible to tailor injection timings and durations to actually control peak cylinder pressures. It should also be possible to detect when nitrous is turned on, so that injection timing is retarded and fueling is increased just about when the nitrous starts going into the cylinders; you'll have decent power for spooling up, but won't over-pressure the cylinders when the nitrous comes on.