Most of my winter prep involves putting stuff
in the cab, not fiddling with the truck itself. Other than having to wait for the "Wait to Start" light to go out, I haven't noticed anything different for winter operation.
Mud/snow rated tires help more than all-season, but unless you're planning to be in snow deeper than a few inches, or off-road snow, it's not that big a deal. I like to carry the same spare parts and engine tools as summertime, and I throw in a few blankets, spare socks, farm boots, spare gloves, two window scrapes, extra flares, small shovel, a few powerbars, etc. Never had to use them for myself, but it's nice to have a spare set of gloves and a shovel, if someone else is stuck without a clue or gear. Nice to have dry socks, too, after you get your feet wet playing in the snow.
Like JW said, get some snow practice in the truck, even if you've driven in snow before. Your big truck will handle differently than other vehicles do, and it's nice to learn how, before it becomes critical. If you put weight in the bed, secure it so it can't move at all. Too many winter truck accidents result in sandbags being thrown through the window into the cab.
I get lots of dirty looks and flashed lights, when I drive down slick hills slower than some flatlanders would like. Don't let anyone rush you or make you uncomfortable. If they didn't want to be late, they should've left earlier.
-jon-