cdrider, I just did this install recently myself and learned a few things...
My advice would be to do one at a time. Bill Babcock (TDR handle drives mopars) did his this way. When he was done he restarted with out having to bleed the injectors at all. It did run rough for a while before smoothing out and purging some air - but it did fire right up.
Here's what I did... . I started out with the mindset of doing one at a time but once I got started I discovered that Cummins had given me the wrong crush washers. My wife was nice enough to run back to Cummins for me to get the right ones. While she was gone I figured I'd make the most of my time and went ahead and pulled all six. Eventually got the new injectors in just fine but when I went to restart - no go! Lot's of air in the lines. It took me a couple of hours to figure out how to bleed them right and run the battery down twice before she finally started off.
Here's a couple of pointers that I learned in this process:
1. ) Take the extra time to loosen/remove some of the injector line hold down clamps and even a valve cover or two when installing the injectors. It will make the job alot easier and put far less bending stress on the lines. Bending the lines will fatigue and weaken the metal. These lines carry fuel at
very high pressure and I for one want to see them remain strong.
2. ) Get all new Banjo clip washers and an extra Banjo bolt or two. If you drop one they are hard to find... .
3. ) If you have to bleed the lines and you live in a cold area plug the truck in for a while first. The combination of the grid heater going on and off and the cranking will kill the battery in nothing flat.
4. ) Bleed several lines at a time. I tried bleeding one at a time, I tried bleeding them all together. It wasn't until I cracked two or three lines at a time and they were all spitting fuel before I got close to starting the truck as I tightened each one down.
5. ) You will find that to get several injectors spitting fuel and purged enough will take you very close to the maximum recommended cranking time or just slightly beyond it. Just give plenty of rest between crankings so things can cool down.
6. ) Lastly don't do this on an asphalt driveway. All that diesel fuel dripping down the motor and on to the asphalt will eat it away.

I have a bunch of little craters now in my driveway to prove it. This is incidently why the pads at gas stations are always concrete!
Good luck! The injectors are worth the effort for sure! Oo.
Ken