Of course it would effect the empty ride. But valving is not black magic like some want us to believe. All drivers are different and some even want to create a different ride.
The conclusion being try it! If you like it keep it, if not try a different valve stack. Its cheap! The hard part is crawling under the truck to pull the shocks off. Sourcing nitrogen for a refill may take some work but you did that when you put the system on so I'm sure you could find nitrogen.