Here's what Blue Chip Diesel has to say:"We proved on a dynomometer in 1998 that if you have 5 PSI, under load, you can make all the power available from a VP44, and 5 psi will provide plenty of return fuel for pump lubrication. We do not recommend running more than 12-15 PSI as that does NOT help the fuel system in any way. In fact higher pressures could diminish fuel delivery to the rotor and make the truck run worse at high RPM and possibly overheat and damage the fuel bypass solenoid. "
My fuel system is setup not to go below 12psi @ WOT but that's just me.
Mike