I had a 99 3500 dually that lost the pocket bearing between the input shaft and the main shaft. . NV5600 -- made a mess of both shafts, and the 5-6 sycro assembly... But this trans was an early one, with the smaller input shaft and smaller sycro rings...
This is the only failure I have heard of , other then major power abuse. .
5600 needs special lube ,,, and is very important , regular 80-90 gear oil is to thick for close tallerance and will over heat , cause bearings to shell out...
my 2. 5 cents. .
Terry