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I am assuming the voltage you are measuring is with the trailer disconnected.
" " " " the "mysterious" 2.1vdc is sensed on blade 3 - Tail/Running lights on the truck's connector.
The voltage to illuminate the tail/running lights comes from the Trailer Tow Relay in the PDC when the lights are turned on.
The battery supplied 12vdc on blade 4 comes from a fuse, 40A Fuse 8 in the PDC which branches/parallels to the contacts of the Trailer Tow Relay to blade 3 via Joint Connector 2 in the PDC.
Blades 3 and 4 are in close proximity and "may" have a stray strand, or foreign material/moisture bridging a high resistance circuit between the conductors in the shell of the connector..
Equally possible is chafed insulation between the two conductors (wires).
Since blades 3 and 4 are from essentially the same 12vdc potential point, with the Trailer Tow Relay contacts breaking the circuit for blade 3 when the lights are turned off, an assumption would indicate that a stray voltage is making its way to the conductor (wire) at or after the Trailer Tow Relay.
I would remove the fuse that supplies the battery voltage to blades 3 and 4, (Fuse 8, 40A in the PDC) then using an ohmmeter check the continuity between blades 3 and 4. It should read an open circuit. If there is any continuity you have a short between conductors/wires.
Replace fuse removed earlier.
Swap relays in the PDC (I believe they are all the same relay number, so any relay will work in the swap). There may be issues with the contacts not fully opening when the relay's coil is de-energized.
Hopefully somewhere in the mess above it will get resolved.