The torque spec depends on the rearend your truck has. Dana 80 (2500 manual trans and all 3500's) requires 450 ft-lb. The 70 (2500 automatic trans) is less.
BUT, mark the relationship of the nut on the pinion shaft before you remove it. When you reinstall it, tighten it SLIGHTLY past the orginal point. This does work on the 80, I think it works on the 70. Doesn't work on any rear end with a crush sleave type set up.