Wow, thanks for all the replies everyone. I hope you all had a Merry Christmas!

Let's see if I can address the various points you all have brought up . . .
Bob4x4: I have pressure-checked the intake system a couple times hoping to find a boost leak or something that might be causing my symptoms, but I haven't been able to hear any leaks. I have a fuel pressure guage and it reads within spec at idle. It has been a few psi low at no-load 2500 RPM lately, so after I change my fuel filter I'll see what the reading says.
Fortunate1: you're exactly right about the uncorrected odometer showing lower miles than actual with 235/85s. When I checked it on an odometer test section of road after I changed tire sizes, the closest I could figure was that it read about . 05 mile low per mile. I have taken that into my calculations.
Hammer: I have replaced my fuel supply and return hoses from the frame to the engine, the section of return hose under the intake manifold that you mentioned, and the 90 degree elbow from the top of the fuel strainer/heater mount to the lift pump, all about a year and a half ago. I used Larry B's marine fuel hoses. My fuel preheater was leaking fuel at the plug a year ago, so I removed the entire preheater. I couldn't tell any improvement after I did that, but at least that is one less factor in the equation. I have not checked under the rubber boot on the fuel primer button on the lift pump, so I will check that. Thanks for the offer to compare your 215 injectors with mine--I will keep that in mind if further troubleshooting fails to turn anything up on mine.
GAmes and Vaughn: I have been eyeing DDP's Stage I injs, but like you say, it would take a lot of miles to recoup the cost solely in fuel savings. Especially if they actually do give you 50 hp more . . .
I have not really done anything to the fuel system on the tank end of things. Do you think it is worth trying to drop the fuel tank (I'd rather raise the bed, but I have a heavy toolbox and a 100-gal tank in the back) to check the pickup tube and the hose fittings on the top of the fuel module? Everybody talks about the air leak problems up at the front end of the fuel system, but I guess there could be problems on the back side too.
Thanks a bunch for all your input. I was afraid at first that this thread was headed for the rocks . . . :-laf I really do appreciate your responses!
CTD12V