You can certainly post to some of the more experienced guys on here but believe me they are all integral.
One changes the other and so on.
I absolutely do NOT know it all, in fact far from it.
I have learned that if you mess with one, expect something else to change, and not always in a good way.
Timing is important when 'up-fueling', it reduces smoke, helps to compensate for the timing effect that installing diff. injectors have.
eg: if your new injectors have a higher pop-off pressure then that will change where/when the fuel is injected,how long that process takes, plus a richer fuel mixture. Timing changes will affect smoke, EGT's and performance. And so it goes. I'd love to see one of the other fella's add to this thread. Perhaps Piers would be good to jump in here.
FWIW.
Regards, Bob