I posted this on another thread, but it is applicable here.
Your mileage will improve to a certian point as the engine breaks in. One note that should be thought about, is that these truck are designed to pull. If you look at the HP / TQ curves against the MPH you will noticed that the optimal speed for these outfits is between 60 and 65, which falls in line with normal towing speeds. If you have your truck Dynoe'd, pay attention to where your peak TQ is in relation to your RPM, then when you are cruising, put your speed inline with the RPM for peak TQ and watch your mileage. I have a 2nd Gen. My peak TQ is at 1,500 rpm which falls in line with 55 mph. At that speed I get 24 mpg. At 70 mph my rpm is 2,000 and my mileage falls to 17. 5. At 65 mph my rpm is 1,800 and I average 22 mpg. At 65 mpg with a 7,000 lb car hauler I get 18 mpg on flat level ground. The trip computer is always off by one or two mpg. I always cacluate by hand. When I fill the tank, I top it to the bitter edge where not another drop will go in.
Hope this helps you in your figuring.