Desert Eagle
I have a 44 & 50 Desert Eagle (Magnum Research) and I love the guns. They have both had many rounds thought them (well into the 5,000+ range). The cost of 50 shells is a rip-off. If I din't have a shooting partner that reloaded, I would never shoot it as much.
The 44 is shot often by my wife (125lbs). The bark is worse than the bite. The recoil is very low. The only draw back is the eagles have a fairly large hand grip. I am 6-3 and the wife is 5-10, she has a little trouble but not bad.
By the way, I have a 10" barrell / 5 clips / and about 700 rounds for the 41 cal eagle I sold. If there is anybody with a 41, give me a pm.