I've been in the OEM business for the last 18 years. The policy is always to REPLACE any locking fastener once removed. This applies to nylock, deformed thread, split nut, and crown nuts. If you open a fastener held by Loctite, it must be cleaned and new liquid applied.
Here's the way I do it at home. If the fastener is obviously ruined on disassembly, I either replace it or use Loctite. If not visibly damaged, I use my fingers to tell me if the locking feature is still working. Many times I still use a shot of Loctite. Nylocks due tend to loose it faster than deformed thread style lockers.
My 2 reale (bits)
John