I think what I've seen and this is just from memory, not a search, is that a lot of guys will leave the kitty and take out the muffler. The cat mellows things out but you still get some serious noise. If I wanted a "straight pipe" setup, that's what I would do.
I have an aftermarket muffler that has been in place for over 150K. It sounds nice, but I really can't hear it much even with the windows down. So that's why I pulled the cat. First I had a straight pipe in place of the cat but the drone was terrible. Sound was phenomenal, but drone was unbearable. So I got another 4" straight thru glasspack style muffler and installed it where the cat used to be. That helped, but I still prefer the lack of noise I had before. For empty driving it's perfect. I can tool along quietly in the cab and make noise if I want to. With a trailer behind it gets a little old on those 12 hour days.