as long as its meant for the new emmissions and the ulsd fuel it wont hurt it at least. the older additives are not compatible with the new engines and can damage them. if that part is good then it cant hurt anything.
as for any gain, thats been a hot topic here for a long time. there are people on both sides and it depends on who you talk to. personally i like additives i have my personal favorite brands, and it makes me sleep better at night. do whatever makes you feel right.