This is kinda interesting!! I always thought they tightened up cause the seats wore down faster thatn the stems.
As a matter of fact when I did mine about a year ago the reason I did it was cause I could hear a poop poop poop from the air intake,, which I think was caused by one of the intakes too tight and not letting the valve close.
Anyway the noise went away after adjustment.
Had that been an exhaust valve it would have been badly burned. So,, the moral is 21k might be a little conservative but these long milages are not good either!
This all brings up the original question. On these newer engines isn't the injection done by a cam driven injector. Does that mean timing should be set periodically also?