I don’t see how excess pressure and fuel would cause damage, especially with the pressure regulator and fuel flow back.
If you have ever taken apart a VP44 for yourself, then you'll see the chamber where the fuel first enters the VP44. The hole that the fuel flows into is very small... cavitation seem evident. I cannot see the need to get 20psi + to try and p*ss through this little hole.
I looked at that a long time ago and this is why I will not run a 2-pump system.