Pipe resonace or vibration
What you guys are hearing is the exhaust pipe itself vibrating in concert with the engine vibrations at those certain rpm's.
The reason it can just develope is that the rubber mounts get softer over time, and the weather is warming up. These combined makes the 'hold' on the exhaust system weaker and allows it to whip or vibrate easier .
The engine vibration is greater when under load, so the pipe also vibrates more when you are towing or under load.
The suggestion to block the system and see if it changes is a very good idea.
Do a search for Drone or Dreaded Drone and sit down with a beverage for a long read, this is a common problem.
The best way to 'fix' it is to change the mass or resonance frequency of the pipes. Clamping on angle iron has been done with some success.
I changed the system to a very heavy pipe [1/8" wall] and this eliminated the drone. [in my truck at least]
Our engine makes a different sound, I like to call it a groan of power, it is the combination of intake noise, exhaust noise [NOT exhaust pipe] and the engine straining under load. This sound is not annoying anywhere near as much as the 'Dreaded Drone'
Hope this helps
Greg L. The Noise Nazi