I would echo the fact of extra filters, I usually carry two to three with me in my tool box, but I did that even before I started using bio. Also I think it would depend on how old of a diesel you have depending weather or not there's going to be much crud break loose and clog the fuel filter up at first using the bio. I may be wrong about that though I don't know but, I'm on my third tank of B20 and so far so good,no filter clogging problems yet. Will fill up again Friday with tank #4, I usually change out the fuel filter every 10K so I like about 3K miles before change out unless I'm forced to from it stopping up :-laf .
Tony