I'm going to stay out of this debate but I'll just jump in real quick and point out that everyone needs to compare apples to apples... some folks in this thread have 3. 55 gears, some have 4. 10, some have 12v, some have 24v, and the last poster had a 3rd gen truck (and 3. 73 gears)... all these variables affect when you need to shift... I for one will run my '01 3500 right up to the redline (while towing at GCWR) when I know it will give me an additional 2MPH (over being a gear higher)... . even though I know my MPG is probably dropping by 5MPG. 
