I assume the truck doesn't have a fuel pressure gauge. It worth having one installed.
Loaded or empty? What RPM? 5-speed or 6-speed transmission? Automatics are 4-speed.
A clogged fuel filter will cause problems but usually it will stumble from a lack of fuel.
In 5th gear at 60 mph the engine RPM will be low and there won't be much turbo boost. That will limit any get up and go.