I agree. We had a couple dozen 6. 6's in late '80's F650 doing varoius jobs. It was a good engine. I always thought it looked like the old standby 300 six gasser. It was a smoker though. Perhaps common rail technology would have done the trick.
Just today I may have a problem with our only F550 6. 7. I had just performed it's winterization PM which includes all engine and hydraulic filters. There are 2 Fuel filters. The primary/ water separator is inside the left frame, mid ship. It's a decent design (MUCH better than the last version) with a vertical bowl that unscrews and element inside. The secondary is what looks like a sized up Asian sealed fuel filter with two quick connect nipples. There is no way to pre fill this. I'm thinking since this is a common rail system, I would recover well. I cycled the key a few times, and was able to hear the pump just like on our Dodges. I got it to start after a couple of cranking attempts- nothing really strange. Now I have on the data display "low fuel pressure" and "reduced power". Indeed the engine is in derate and was barely able to get it out of the bay. I will have to further investigate Monday.
I have done hundreds of filter changes like this and NEVER had a problem like whats happening. If there was air, the engine would just shrug it off and be fine... If there is a special procedure to change a fuel filter, it's not in the owners manual or obvious anywhere else. This truck is NOT shade tree friendly for even the most basic maintenance.