Injectors have no effect, good or bad, on the injection pump.
A mild box stays within stock parameters, so I'd say that it also has no effect on the pump.
A fueling box that connects to the VP will tax the pump, but it depends on how aggressively the box is set up. The VP44 is used in many other applications besides the CTD, and the duty cycle in some applications exceeds what the CTD is.
So there's a little headroom, but the VP does have its limits, and most fueling boxes are pushing them.
Justin