Its also about longevity,in a pickup these engines are loafing for the most part,only a few are towing upwards of 30K GVWR all the time. In an F750 the truck is sitting at 15K dry with a huge frontal area,and they run 30K-35K most of the time,if they arent overloaded,then some guys tow 20-30K trailers with them too,so these engines will not last like they do in a pickup. They may be running at 50KGVWR+ for days on end ,wide open. I drove MD trucks for a little while,it has been my experience that you literally are flatfooted 90% of the time. We ran our 35K GVWR F800 Ford (3208 CAT)wide open all the time,and we loaded it to 40K constantly. I also towed an excavator with it,on a 15 ton trailer,so these trucks take a lot more of a beating than our pickups do,IMO. So these engines need to be detuned a bit to last with foot to floor all the time. In addition,the biggier engines wouldnt sell as well if the smaller ones made the same power,were cheaper,and the truck could carry more weight because of the lighter engine.